Passive stiffness of the heart is determined largely by extracellular matrix and titin. which functions as a molecular spring within sarcomeres. Titin stiffening is associated with the development of diastolic dysfunction (DD). while augmented titin compliance appears to impair systolic performance in dilated cardiomyopathy. https://www.bekindtopets.com/top-sale-Granular-foveolae-3911-limited-choice/